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WHAT IS IT?
Isotretinoin (Claravis, Accutane, Roaccutane) is a synthetic retinoid (vitamin A derivative).
WHEN DO WE USE IT?
Severe acne: this medication is an anti-acne drug.
WHEN DO WE AVOID USING IT?
During pregnancy: this medication is a known teratogen.
Patients not on birth control: patients must be on 2 forms of contraception for at least 1 month prior to beginning treatment. These contraceptives must be used during the course of treatment, and even 1 month after isotretinoin is discontinued.
HOW IS IT ADMINISTERED?
Administer orally twice a day with meals. Take with a full glass of liquid to avoid esophageal irritation. Do not suck/chew capsules.
WHAT ARE THE SIDE EFFECTS/TOXICITY?
Teratogenic effects: this medication is known to cause many congenital abnormalities if used during pregnancy:
- Craniofacial dysmorphism
- Heart defects
- Deafness
Esophageal irritation: this mediation can irritate the esophagus if it is not taken with a full glass of liquid, is sucked, or the capsule is chewed during administration.
ANYTHING ELSE TO KEEP IN MIND?
FURTHER READING
Page Updated: 10.15.2016