Pertussis

OVERVIEW

Pertussis (whooping cough) refers to a respiratory illness that is caused by the Bordetella pertussis bacteria. It is a highly infectious form of bronchitis.

Pertussis is characterized by its distinctive "whooping cough" (source)
Pertussis is characterized by its distinctive “whooping cough” (source)
WHAT MAKES US SUSPECT IT?

Risk Factors:

Young infants ( < 6 months old)

Initial Presentation:

  • Prolonged cough ( can last for > 2 weeks)
  • Episodes of coughing
CLINICAL WORKUP

Complete Blood Count (CBC):

  • Elevated white count (lymphocytosis) may be observed (caused by pertussis toxin)

Chest X-Ray: perihilar infiltrate/edema can sometimes be seen on a chest X-ray.

Immunofluorescence (IF): testing of nasopharyngeal secretions with IF can help make this diagnosis.  

PCR: PCR testing of a swabbed sample (nasopharyngeal secretions) can help make this diagnosis.

HOW DO WE PREVENT IT?

DTaP Vaccine/DTP Vaccine: these vaccines are used to prevent the development of this condition.

Pertussis post-exposure prophylaxis:

ARCHIVE OF STANDARDIZED EXAM QUESTIONS 

This archive compiles standardized exam questions that relate to this topic.

Page Updated: 11.14.2016