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OVERVIEW
This page is dedicated to organizing various examples of standardized exam questions whose answer is bullous pemphigoid. While this may seem a odd practice, it is useful to see multiple examples of how bullous pemphigoid will be characterized on standardized exams (namely the boards and the shelf exams). This page is not meant to be used as a traditional question bank (as all of the answers will be the same), however seeing the classic “test” characterization for a disease is quite valuable.
KEY CHARACTERISTICS OF THIS CONDITION (ON EXAMS)
When it comes to standardized exams, each condition has its own “code” marked by key buzzwords, lab findings, clues, etc. If you are well versed in this code you will be able to more quickly identify the condition that is being discussed, and get the right answer on the exam you are taking. Below is the “code” for bullous pemphigoid.
- Bullae: tense blisters are characteristic. Affect skin but spare oral mucosa.
- Sub epidermal in their location (seen on histology)
- Immunoflorescance reveals linear pattern at epidermal/dermal junction.
QUESTION EXAMPLES
Question # 1
Explanation # 1
Question # 2
Explanation # 2
TESTABLE FACTS ABOUT THIS CONDITION (BEYOND ITS IDENTIFICATION)
Many questions on standardized exams go beyond simply recognizing the underlying condition. Often there are specific testable facts regarding some aspect of the disease’s pathophysiology/management/clinical implications that are commonly asked. Some of these are listed below::
- What causes it: auto-antibody against hemidesmosomal proteins (IgG anti-hemidesmosme) at the basement membrane.
- What do hemidesmosomes do: connect keratin in basal cells to the underlying basement membran
- Where are the bullae: below the epidermis
Page Updated: 02.15.2017