Clevidipine

WHAT IS IT?

Clevidipine (Cleviprex) is a calcium channel blocker.

WHEN DO WE USE IT?

Hypertensive emergencies,

WHEN DO WE AVOID USING IT?
HOW IS IT ADMINISTERED?
HOW IS IT DOSED?

Infusion:

  • Initial dose: 1-2 mg/hour
  • Titration:  For every 1 to 2 mg/hour increase in dose, an approximate reduction of 2 to 4 mm Hg in SBP is expected.
  • Maintenance dose: 4-6 mg/hour
  • Maximum dose: 21 mg/hour (most patients kept < 16 mg/hour)

* No dosing adjustments for hepatic or renal impairment 

WHAT ARE THE SIDE EFFECTS/TOXICITY?
ANYTHING ELSE TO KEEP IN MIND?

 

Page Updated: 07/17/2018