Fluphenazine

WHAT IS IT?

Fluphenazine (Prolixin) is a high potency first generation (typical) antipsychotic. It is a potent dopamine D2 receptor antagonist.

WHEN DO WE USE IT?

Schizophrenia

Psychosis that is due to other causes

WHEN DO WE AVOID USING IT?
HOW IS IT ADMINISTERED?
WHAT ARE THE SIDE EFFECTS/TOXICITY?

Extrapyramidal symptoms are more common in this high potency D2 antagonist.

  • Acute dystonia
  • Akathisia
  • Parkinsonism
ANYTHING ELSE TO KEEP IN MIND?
FURTHER READING

DynaMed

UpToDate

 

Page Updated: 09.14.2016